Relationship between plasma omentin-1 levels and newly diagnosed Stage I hypertension

Aim: Omentin-1 is an adipose tissue-derived cytokine with unknown biological function. The impact of omentin-1 on hypertension has been questioned due to its relation to obesity. This study is aimed to investigate omentin-1 levels in hypertensive patients.Material and Methods: A prospective, case-control study evaluated patients admitted to outpatient cardiology clinics between January 2012 and December 2013. We designed two groups: the patient group comprised hypertensive patients with newly diagnosed stage-1 hypertension, and the control group comprised normotensive patients. The demographic and anthropometric characteristics and laboratory parameters of the patients in both groups were recorded. Plasma levels of omentin-1 were the primary outcome in this study. Results: Patient group consisted of 52 hypertensive patients, whereas the control group consisted of 36 patients without hypertension. There was no significant difference between the groups in terms of demographic and clinical characteristics (p>0.05). The median omentin-1 level of the patient group was higher than that of the control group (756.2 ng/mL vs. 664.4 ng/mL); however, the difference was insignificant (p=0.161).Discussion: The findings of this study did not suggest a significant relationship between the plasma omentin-1 levels and the newly diagnosed Stage hypertension.