Glabridin inhibits liver fibrosis and hepatic stellate cells activation through suppression of inflammation and oxidative stress by activating PPARγ in carbon tetrachloride-treated mice

•Glabridin attenuated the liver injury and liver fibrosis in CCl4-treated mouse livers.•Glabridin increased the expression of PPARγ in CCl4-treated mouse livers.•Glabridin inhibited the inflammation and oxidative stress in CCl4-treated mouse livers.•Glabridin suppressed the PDGF-BB-stimulated activation of JS-1 cells and liver fibrosis in vitro.•Disruption of PPARγ attenuated the anti-inflammatory and anti-oxidative stress effects of glabridin in stimulated JS-1 cells.