Biologic Evaluation of a Heterodimeric HER2-Albumin Targeted Affibody Molecule Produced by Chemo-Enzymatic Peptide Synthesis.

Yongsheng Liu,Rezan Gueler, Yunqi Liao,Anzhelika Vorobyeva,Olof Widmark,Theodorus J. J. Meuleman,Anna Koijen,Leendert J. J. van den Bos, Robert Naasz,Vitalina Bodenko,Anna Orlova,Caroline Ekblad,Vladimir Tolmachev,Fredrik Y. Y. Frejd

Pharmaceutics（2022）

Cited 0|Views12

Key words

Affibody molecule,albumin binding domain (ABD),peptide synthesis,enzymatic ligation,scaffold protein,radionuclide therapy,Lu-177,DOTA,SKOV-3 xenograft,biodistribution

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