Comparative efficacy and safety of monoamine oxidase type B inhibitors plus channel blockers and monoamine oxidase type B inhibitors as adjuvant therapy to levodopa in the treatment of Parkinson's disease: a network meta-analysis of randomized controlled trials.

Rui Yan,Huihui Cai,Yusha Cui,Dongning Su,Guoen Cai,Fabin Lin,Tao Feng

European journal of neurology（2023）

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摘要

Monoamine oxidase type B inhibitors plus, conventional MAO-BIs and the corresponding doses are similar in efficacy in PD treatment. MAO-BIs plus might be safer than conventional MAO-BIs. Head-to-head comparisons are needed for further investigation.

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关键词

MAO-B inhibitors,Parkinson disease,ion channel blockers,levodopa,network meta-analysis

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