The Associations Between Intracranial Stenosis, Brain Amyloid-beta, and Cognition in a Memory Clinic Sample.

Mervyn J R Lim, Jaclyn Tan,Bibek Gyanwali, Tomotaka Tanaka,Anthonin Reilhac, Henri A Vrooman,Christopher Chen,Saima Hilal

Alzheimer disease and associated disorders（2022）

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摘要

ICS was significantly associated with worse cognition and showed interaction with brain Aβ such that patients with both pathologies performed worse on visuomotor speed specifically in those without dementia. Further studies may clarify if ICS and brain Aβ deposition indeed have a synergistic association with cognition.

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