Periodontal ligament-associated protein-1 engages in teeth overeruption and periodontal fiber disorder following occlusal hypofunction.

Yilin Chen,Mengqi Luo,Yaxin Xie,Lu Xing,Xianglong Han,Ye Tian

Journal of periodontal research（2023）

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摘要

PLAP-1 presumably plays a pivotal role in occlusal force-regulated periodontal homeostasis by facilitating collagen fiber synthesis in hPDLCs and suppressing excessive osteoblast differentiation, further preventing teeth from overeruption. Further evidence in PLAP-1 conditional knockout mice is needed.

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关键词

Flexcell FX-5000 compression system,PLAP-1/asporin,alveolar bone,fiber disorder,occlusal hypofunction,overeruption,periodontal ligament

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