Glucagon-like Peptide-2 Acutely Enhances Chylomicron Secretion in Humans Without Mobilizing Cytoplasmic Lipid Droplets.

Majid Mufaqam Syed-Abdul,Priska Stahel,Alyssa Zembroski,Lili Tian,Changting Xiao,Avital Nahmias,Ian Bookman,Kimberly K Buhman,Gary F Lewis

The Journal of clinical endocrinology and metabolism（2023）

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摘要

Unlike glucose that mobilizes enterocyte CLDs and enhances CM secretion, GLP-2 acutely increased plasma CMs without significant mobilization of CLDs, supporting our previous findings that GLP-2 does not act directly on enterocytes to enhance CM secretion and most likely mobilizes secreted CMs in the lamina propria and lymphatics.

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关键词

chylomicrons,dyslipidemia,glucagon-like peptide-2,intestine

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