Sustained release of locally delivered celecoxib provides pain relief for osteoarthritis: a proof of concept in dog patients.

A R Tellegen,I Rudnik-Jansen,L Utomo, S Versteeg,M Beukers, R Maarschalkerweerd, D van Zuilen, N J van Klaveren, K Houben,E Teske,P R van Weeren, N Karssemakers-Degen,G Mihov,J Thies,N Eijkelkamp,L B Creemers, B P Meij,M A Tryfonidou

Osteoarthritis and cartilage（2022）

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摘要

These results show that local sustained release of CXB is less suitable to treat acute inflammation in arthritic joints, while safe and effective in treating pain in chronic OA in dogs.

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关键词

Controlled release,Inflammation,Non-steroidal anti-inflammatory drugs,Osteoarthritis,Pain

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