C-N bond cleavage of primary amine for the synthesis of multi-substituted pyridine and pyrrole derivatives

An efficient synthesis of multi-substituted pyridines and pyrroles has been developed from aryl methyl ketones with 1-amino-2-methylpropan-2-ol and 1,2-diamino-2-methylpropane, respectively. The reaction involves one C-N bond cleavage and two new...