Fusobacterium nucleatum induces colon anastomosis leak by activating epithelial cells to express MMP9.
Frontiers in microbiology(2022)
Abstract
This work demonstrates that attaches and then stimulates the expression of epithelial cells MMP9 by the E-cadherin/β-catenin signaling pathway. These effects contribute to collagen break down in the intestinal tissue, finally leading to AL.
MoreTranslated text
Key words
Fusobacterium nucleatum,adhesion ability,anastomotic leak,colorectal cancer,matrix metalloproteinase 9
AI Read Science
Must-Reading Tree
Example
Generate MRT to find the research sequence of this paper
Chat Paper
Summary is being generated by the instructions you defined