Increased Pro-Inflammatory T Cells, Senescent T Cells, and Immune-Check Point Molecules in the Placentas of Patients With Gestational Diabetes Mellitus.

Yea Eun Kang,Hyon-Seung Yi,Min-Kyung Yeo,Jung Tae Kim, Danbit Park, Yewon Jung, Ok Soon Kim,Seong Eun Lee,Ji Min Kim,Kyong Hye Joung,Ju Hee Lee,Bon Jeong Ku,Mina Lee,Hyun Jin Kim

Journal of Korean medical science（2022）

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摘要

This study demonstrated increased proinflammatory T cells, senescent T cells and immune-check point molecules in GDM placentas, suggesting that changes in senescent T cells and immune-escape signaling might be related to the pathophysiology of GDM.

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关键词

Gestational Diabetes,Immune-Check Point Molecules,Placenta,RNA-Sequencing,Senescent T Cells,T Cell Immunity

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