Replacement of SARS-CoV-2 strains with variants carrying N501Y and L452R mutations in Japan: an epidemiological surveillance assessment br

Yusuke Kobayashi,Takeshi Arashiro,Miyako Otsuka,Yuuki Tsuchihashi,Takuri Takahashi,Yuzo Arima,Yura K. Ko,Kanako Otani,Masato Yamauchi,Taro Kamigaki,Tomoko Morita-Ishihara,Hiromizu Takahashi,Sana Uchikoba,Michitsugu Shimatani,Nozomi Takeshita,Motoi Suzukia,Makoto Ohnishi

WESTERN PACIFIC SURVEILLANCE AND RESPONSE（2022）

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摘要

In Japan, Alpha and Delta variants displayed regional differences in the replacement timing and their relative transmission advantages. Our method is efficient in monitoring and estimating changes in the proportion of variant strains in a timely manner in each region.

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l452r mutations,sars-cov

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