Assessment of mouse VEGF neutralization by ranibizumab and aflibercept.

Yusuke Ichiyama,Riko Matsumoto,Shumpei Obata,Osamu Sawada,Yoshitsugu Saishin,Masashi Kakinoki,Tomoko Sawada,Masahito Ohji

PloS one（2022）

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摘要

Aflibercept but not ranibizumab interacts with mouse VEGF, both in vivo and in vitro. When conducting experiments using anti-VEGF drugs in mice, aflibercept is suitable, but ranibizumab is not.

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关键词

mouse vegf neutralization,ranibizumab

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