Tricholosterols A-D, Four New Ergosterol Derivatives from the Mushroom Tricholoma Terreum
Steroids(2023)
摘要
Four ergosterol derivatives, named tricholosterols A-D (1-4), have been isolated from the fruiting bodies of Tricholoma terreum. Their chemical structures have been determined using a combination of spectroscopic analysis as well as computational methods. Compound 1 possesses a rare D-ring opening ergosterol skeleton, while compounds 2-4 are rare degraded ergosterols. Compounds 1 and 4 exhibited moderate inhibitory activity against NO production with IC50 values of 27.6 and 31.8 mu M, respectively. This is the first report of steroids from T. terreum.
更多查看译文
关键词
Tricholoma terreum,Ergosterol derivatives,NO production inhibition
AI 理解论文
溯源树
样例
生成溯源树,研究论文发展脉络
Chat Paper
正在生成论文摘要