Safety and Tolerability of Oral Cannabinoids in People Living with HIV on Long-Term ART: A Randomized, Open-Label, Interventional Pilot Clinical Trial (CTNPT 028).

Ralph-Sydney Mboumba Bouassa,Judy Needham, Dana Nohynek,Joel Singer,Terry Lee,Florian Bobeuf,Suzanne Samarani,Lina Del Balso, Natalie Paisible, Claude Vertzagias,Giada Sebastiani,Shari Margolese,Enrico Mandarino,Marina Klein,Bertrand Lebouché,Joseph Cox,Marie-Josée Brouillette,Jean-Pierre Routy,Jason Szabo,Réjean Thomas, Emmanuel Huchet,Antonio Vigano,Mohammad-Ali Jenabian,Cecilia T Costiniuk

Biomedicines（2022）

引用 6|浏览26

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摘要

In PLWH, cannabinoids seem generally safe and well-tolerated, though larger studies are needed. Screening for occult liver pathology should be performed and hepatic enzymes monitored, especially with high CBD doses.

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关键词

HIV,cannabidiol (CBD),cannabinoids,chronic liver diseases,pilot clinical trial,quality of life,tetrahydrocannabinol (THC)

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