Efficacy and safety of cilostazol in decreasing progression of cerebral white matter hyperintensities-A randomized controlled trial.

Bonaventure Y M Ip,Bonnie Y K Lam, Vincent M H Hui,Lisa W C Au, Mandy W T Liu,Lin Shi,Vivian W Y Lee,Winnie C W Chu,Thomas W Leung,Ho Ko,Vincent C T Mok

Alzheimer's & dementia (New York, N. Y.)（2022）

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摘要

In this trial with stroke- and dementia-free subjects with confluent WMHs, cilostazol did not impact WMH progression but demonstrated an acceptable safety profile. Future studies should address the treatment effects of cilostazol on subjects at different clinical stages of SVD.

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关键词

brain,cerebral small vessel diseases,cilostazol,clinical trials,dementia,intention‐to‐treat analysis,magnetic resonance imaging,white matter

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