STRA6 Promotes Thyroid Carcinoma Progression via Activation of the ILK/AKT/mTOR Axis in Cells and Female Nude Mice.

Weiman He,Zhen Cheng,Zijun Huo,Bo Lin,Xuejie Wang, Yijia Sun,Shuang Yu,Siting Cao,Junyu Xue,Rengyun Liu,Weiming Lv,Yanbing Li,Shubin Hong,Haipeng Xiao

Endocrinology（2023）

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摘要

Our study demonstrates the critical roles of STRA6 contributing to TC progression via the ILK/AKT/mTOR axis, which may provide a novel prognostic marker as well as a promising therapeutic target for aggressive TC.

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关键词

ILK/AKT/mTOR axis,STRA6,lipid metabolism,nanoparticle,thyroid carcinoma

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