Fabrication of novel polysaccharide hybrid nanoliposomes containing citral for targeting MRSA-infected wound healing

•The synthesized CMC/PA/Cit-NLPs exhibited good biocompatibility.•CMC/PA/Cit-NLPs decreased bacterial growth in a MRSA-infected excision wound model.•CMC/PA/Cit-NLPs modulated of inflammatory responses through reducing the expression levels of NF-Kb.•CMC/PA/Cit-NLPs upregulated the fibroblast cells infiltration and collagen type 1A biosynthesis.•CMC/PA/Cit-NLPs accelerated the healing of MRSA-infected excision wound model.