Prevalence, characteristics and outcomes of older patients with hereditary versus wild-type transthyretin amyloid cardiomyopathy

A. Porcari,Y. Razvi,A. Masi,R. Patel,A. Ioannou, M. U. Rauf,L. Venneri,A. Martinez-Naharro,M. Merlo,G. Sinagra,H. Lachmann,A. Wechalekar,P. N. Hawkins,M. Fontana,J. D. Gillmore

European journal of heart failure（2023）

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摘要

Up to 20.7% of elderly patients with ATTR-CM have a pathogenic TTR variant. These findings support routine sequencing of the TTR gene in all patients with ATTR-CM regardless of age. This article is protected by copyright. All rights reserved.

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amyloid cardiomyopathy,elderly,epidemiology,hereditary transthyretin amyloidosis,transthyretin genetic testing

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