Dysregulation of striatal dopamine D2/D3 receptor-mediated by hypocretin induces depressive behaviors in rats.

Bing Chen,Jiangang Xu,Simiao Chen,Tingting Mou,Ying Wang, Haojun Wang,Zhihan Zhang, Feifan Ren,Zheng Wang,Kangyu Jin, Jing Lu

Journal of affective disorders（2023）

引用 2|浏览5

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摘要

Depressive-like behaviors induced by CUMS can be reversed by suvorexant, and the therapeutic effects of suvorexant may be mediated by affecting the dopamine system.

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关键词

Depression,Dopamine system,Hypocretin,NMDAR,Suvorexant

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