An intracerebroventricular injection of AΒ (1–42) modifies temporal profiles of spatial memory performance and oxidative status in the temporal cortex rat

Brain Research(2023)

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摘要
•MDA, protein carbonyls and TAC exhibit a daily variation in the rat temporal cortex.•Spatial memory performance varied rhythmically in the rat.•An injection of Aβ aggregates modifies the rhythms of parameters of oxidative stress in the temporal cortex of rats.•ICV injection of Aβ aggregates in the rat brain caused alterations in the cognitive performance.
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AD,,ANOVA,BSA,GS,ICV,LPO,MDA,NGS,PT,TC,SCN,TAC,TBARS,ZT
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