Specific fungi associated with response to capsulized fecal microbiota transplantation in patients with active ulcerative colitis.

Qiongyun Chen,Yanyun Fan,Bangzhou Zhang,Changsheng Yan,Zhangran Chen,Lin Wang,Yiqun Hu,Qingwen Huang,Jingling Su,Jianlin Ren,Hongzhi Xu

Frontiers in cellular and infection microbiology（2022）

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摘要

In the metagenomic analysis of fecal samples from donors and patients with UC receiving capsulized FMT, shifts in gut fungal diversity and composition were associated with capsulized FMT and validated in patients with active UC. We also identified the specific fungi associated with the induction of remission. ClinicalTrails.gov (NCT03426683).

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关键词

capsule administration,fecal microbiota transplantation,metagenomics,mycobiota,ulcerative colitis

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