Absolute and Relative Vaccine Effectiveness of Primary and Booster Series of COVID-19 Vaccines (mRNA and Adenovirus Vector) Against COVID-19 Hospitalizations in the United States, December 2021-April 2022.

Nathaniel M Lewis,Nancy Murray,Katherine Adams,Diya Surie,Manjusha Gaglani,Adit A Ginde,Tresa McNeal,Shekhar Ghamande,David J Douin,H Keipp Talbot,Jonathan D Casey,Nicholas M Mohr,Anne Zepeski,Nathan I Shapiro,Kevin W Gibbs,D Clark Files,David N Hager,Harith Ali,Matthew E Prekker,Anne E Frosch,Matthew C Exline,Michelle N Gong,Amira Mohamed,Nicholas J Johnson,Vasisht Srinivasan,Jay S Steingrub,Ithan D Peltan,Samuel M Brown,Emily T Martin,Arnold S Monto,Adam S Lauring,Akram Khan,Catherine L Hough,Laurence W Busse,William Bender,Abhijit Duggal,Jennifer G Wilson,Alexandra June Gordon,Nida Qadir,Steven Y Chang,Christopher Mallow,Carolina Rivas,Hilary M Babcock,Jennie H Kwon,James D Chappell,Natasha Halasa,Carlos G Grijalva,Todd W Rice,William B Stubblefield,Adrienne Baughman,Christopher J Lindsell,Kimberly W Hart,Jillian P Rhoads,Meredith L McMorrow,Mark W Tenforde,Wesley H Self,Manish M Patel

Open forum infectious diseases（2023）

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摘要

Vaccine booster doses increased protection against COVID-19 hospitalization compared with a primary series. Comparing rVE measures across studies can lead to flawed interpretations of the added value of a new vaccination regimen, whereas difference in aVE, when available, may be a more useful metric.

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关键词

COVID-19,absolute vaccine effectiveness,booster vaccine series,primary vaccine series,relative vaccine effectiveness

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