Design, Synthesis, Molecular Docking, and Preliminary pharmacological screening of some new benzo[d]thiazol-2-ylamino containing chromen-2-one derivatives with atypical antipsychotic profile.

Current computer-aided drug design(2023)

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摘要
Compounds 4b, 4c, 4e, 4g & 4i have demonstrated promising pharmacological action in preliminary studies. According to the preceding findings, compounds with electron-withdrawing substitutions, such as 4e & 4b, have a good atypical profile of antipsychotics.
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关键词
Anti-psychotics ,Chromen-2-one derivatives as atypical antipsychotic agents.,Coumarin ,Molecular Docking ,Schizophrenia
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