Combined all-trans retinoic acid with low-dose apatinib in treatment of recurrent/metastatic head and neck adenoid cystic carcinoma: A single-center, secondary analysis of a phase II study.

Lulu Ye,Lin Zhang,Rongrong Li,Xinhua Pan,Jiang Li,Shengjin Dou,Wen Jiang, Chong Wang,Wantao Chen,Guopei Zhu

Cancer medicine（2023）

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摘要

All-trans retinoic acid combined with low-dose apatinib might be a potential efficacy therapeutic option for patients with R/M ACCHN. This finding will be further confirmed by our registered ongoing trial, the APLUS study (NCT04433169).

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关键词

adenoid cystic carcinoma,all-trans retinoic acid,apatinib,head and neck cancer,oncological outcomes

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