Metabolomic markers mediate erythrocyte anisocytosis in older adults: Results from three independent aging cohorts.

Journal of internal medicine(2023)

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摘要
This metabolomics study of three independent aging cohorts identified a specific set of metabolites mediating anisocytosis with aging. Whether SDMA, ADMA, and 1-methylhistidine are released by the damaged erythrocytes with high RDW or they affect the physiology of erythrocytes causing high RDW should be further investigated.
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关键词
1-methylhistidine,ADMA,SDMA,aging,metabolomics,red blood cell distribution width
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