Inflammation compared to low-density lipoprotein cholesterol: two different causes of atherosclerotic cardiovascular disease.

Benjamin N Wadström,Kasper M Pedersen,Anders B Wulff,Børge G Nordestgaard

Current opinion in lipidology（2023）

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摘要

IL-6 mediated inflammation most likely causes ASCVD, in parallel with LDL cholesterol. However, fewer individuals in the general population are exposed to high IL-6 than high LDL cholesterol. For inflammation, future research should focus on improving efficacy and safety of anti-inflammatory therapy, and for LDL cholesterol, future research should focus on wider and more effective implementation of LDL cholesterol lowering therapy.

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关键词

low-density low-density lipoprotein,cholesterol,cardiovascular disease,inflammation

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