H&E and OCT4/CD34 for the assessment of lympho-vascular invasion in seminoma and embryonal carcinoma

Costantino Ricci,Francesca Ambrosi,Tania Franceschini,Francesca Giunchi,Maria Eugenia Maracci,Maria Sirolli,Agnese Orsatti,Federico Chiarucci,Eugenia Franchini, Matteo Borsato,Francesco Massari,Veronica Mollica,Federico Mineo Bianchi,Maurizio Colecchia,Andres Martin Acosta,Michelangelo Fiorentino

Pathology - Research and Practice（2023）

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摘要

•The best values of IrOA are obtained by UPs on H&E slides, with OCT4/CD34 not improving the IrOA in all groups.•CD modify the LVI in a significant number of cases, but the effect on the pT re-staging is less relevant.•The main sources of disagreement among UPs are artefactual clefts and histiocytes within the vessels on H&E slides.•The main sources of disagreement among UPs are artefactual clefts and floaters on OCT4/CD34 slides.

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关键词

LVI,GCTT,ISUP,UPs,non-UPs,GCNIS,IrOA,H&E,IHC,OCT4,CD34,SALL4,CD,CD-H&E,CD-OCT4/CD34,S,EC,S-EC,AJCC,RLND,ETS-related gene,D2–40,CD31,LYVE-1,vWF,vs

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