Quantitation of neurofilament light chain protein in serum and cerebrospinal fluid from patients with multiple sclerosis using the MSD R-PLEX NfL assay.

Antigona Ulndreaj,Dorsa Sohaei,Simon Thebault,Oscar D Pons-Belda,Amaia Fernandez-Uriarte,Christopher Campbell,David Cheo,Martin Stengelin,George Sigal,Mark S Freedman,Isobel A Scarisbrick,Ioannis Prassas,Eleftherios P Diamandis

Diagnosis (Berlin, Germany)（2023）

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摘要

We show that MSD's R-PLEX NfL assay can reliably quantitate levels of NfL in the CSF and serum from patients with MS and controls, where levels correlate strongly with Simoa.

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关键词

R-PLEX,Simoa,cerebrospinal fluid,electrochemiluminescence,multiple sclerosis,neurofilament light,serum

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