Is local review of positron emission tomography scans sufficient in diffuse large B-cell lymphoma clinical trials? A CALGB 50303 analysis.

Pallawi Torka,Levi D Pederson,Michael V Knopp,David Poon,Jun Zhang,Brad S Kahl, Howard R Higley,Gary Kelloff,Jonathan W Friedberg,Lawrence H Schwartz,Wyndham H Wilson,John P Leonard,Nancy L Bartlett,Heiko Schöder,Amy S Ruppert

Cancer medicine（2023）

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摘要

These data suggest that local PET interpretation for response determination may be acceptable in clinical trials. Our findings also highlight limitations of VSS and call for incorporation of more objective measures of response assessment in clinical trials.

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关键词

Deauville 5-PS,International Harmonization Project criteria,interim PET,visual scoring system,ΔSUV

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