Longitudinal analysis of DC subsets in patients with ovarian cancer: Implications for immunotherapy.

Beatris Mastelic-Gavillet,Apostolos Sarivalasis,Leyder Elena Lozano,Sebastien Lofek,Tania Wyss,Ignacio Melero,I Jolanda M de Vries,Alexandre Harari,Pedro Romero,Lana Elias Kandalaft,Selena Viganó

Frontiers in immunology（2023）

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摘要

Our study provides new information about the impact of chemotherapy on the immune system of patients with OvC and sheds a new light on the importance of considering timing with respect to chemotherapy when designing new vaccination strategies that aim at withdrawing or targeting specific DC subsets.

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关键词

DC,TLR3,cancer vaccine,chemotherapy,ovarian cancer

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