[Application of fluorescence in situ hybridization technique to verify the clonalities of non-clonal cytogenetic abnormalities identified in Myelodysplastic syndrome].

Zheng Wang,Yanlin Wang,Wenjie Song,Lin Feng,Lu Gao,Ye Li,Xiaojun Huang,Yueyun Lai

Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics（2023）

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摘要

Nearly half of the CBA identified n-CCA have been verified as clonal aberrations by FISH, and the FISH detection rate showed no correlation with the number of metaphase cells. FISH test is strongly recommended for verifying the clonalities of n-CCA detected by CBA, and continuous cytogenetic survey of the patients with MDS is necessary.

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关键词

myelodysplastic syndrome,situ hybridization technique,situ hybridization,fluorescence,non-clonal

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