In vitro susceptibility of nonfermenting Gram-negative rods to meropenem-vaborbactam and delafloxacin.

Future microbiology(2023)

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摘要
Meropenem-vaborbactam and delafloxacin activities were not assessed against spp. (), complex () and (). A total of 106 , 57  and 100  were tested with gradient diffusion test of meropenem-vaborbactam, delafloxacin and comparators. Meropenem-vaborbactam MIC were 4 μg/ml for , 1 μg/ml for , 2 μg/ml for and , and 32 μg/ml for . Delafloxacin MIC were 4 μg/ml for , 0.25 μg/ml for and , 2 μg/ml for , and 0.5 μg/m for . meropenem-vaborbactam MICs were fourfold lower than meropenem for 28.3% , 77.2% , 53.8% and 77.2% . Meropenem-vaborbactam and delafloxacin are active against and .
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关键词
Achromobacter,Burkholderia,Stenotrophomonas,cystic fibrosis,delafloxacin,lung transplant recipient,meropenem,transplantation,vaborbactam
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