DNA methylation profiling reveals novel pathway implicated in cardiovascular diseases of diabetes.

Shengqing Hu,Lulu Chen,Tianshu Zeng, Wenyi Wang,Yan Yan,Kangli Qiu, Yajuan Xie,Yunfei Liao

Frontiers in endocrinology（2023）

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摘要

This study revealed that the hypomethylation of VEGFB, PLGF, PLCB1, and FATP4 might be the potential biomarkers. Besides, VEGFR signaling pathway regulated by DNA methylation might play a role in the cardiovascular diseases' pathogenesis of diabetes.

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关键词

DNA methylation,cardiovascular diseases,diabetes,methylated DNA immunoprecipitation,signaling pathway

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