Efficacy of third-line anti-EGFR-based treatment versus regorafenib or trifluridine/tipiracil according to primary tumor site in RAS/BRAF wild-type metastatic colorectal cancer patients.

Frontiers in oncology(2023)

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摘要
Our results demonstrated a different benefit from third-line anti-EGFR-based therapy according to primary tumor site, confirming the role of L-sided tumor in predicting benefit from third-line anti-EGFR vs R/T. At the same time, no difference was observed in R-sided tumor.
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关键词
RAS/BRAF wild-type,Regorafenib,anti-egfr ab,colorectal cancer,primary tumor site,third-line therapy,trifluridine/tipiracil
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