Real-world palbociclib effectiveness in patients with metastatic breast cancer: Focus on neutropenia-related treatment modification strategies and clinical outcomes.

Mariska Q N Hackert,Cornelia F van Uden-Kraan,Mariette J Agterof,Annette W G van der Velden,Birgit E P J Vriens,Johan J B Janssen, Maud Geenen,Annemieke van der Padt-Pruijsten,Ewoudt M W van de Garde

Cancer treatment and research communications（2023）

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摘要

This study suggests no impact of neutropenia-related treatment modifications on PFS and confirms inferior outcomes outside clinical trial eligibility.

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关键词

Clinical practice,Efficacy-effectiveness gap,Metastatic breast cancer,Palbociclib,Real-world,Treatment modification strategies

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