Hyperferritinemic sepsis secondary to invasive Toxoplasma gondii in a child with untreated HIV.
Boletin medico del Hospital Infantil de Mexico(2023)
摘要
Background:Untreated human immunodeficiency virus (HIV)-immunosuppressed pediatric patients show high morbidity and mortality from opportunistic infections. Limited cases of hyperferritinemic sepsis have been described in patients with toxoplasmosis.
Case report:We describe the case of a 13-year-old female patient with a history of untreated HIV who presented with hyperferritinemic sepsis secondary to Toxoplasma gondii infection and Pneumocystis jirovecci pneumonia. She received ventilatory support, inotropic drugs, treatment for opportunistic germs, and high-dose corticosteroids, but with unfavorable evolution.
Conclusions:The global approach to sepsis with elevated ferritin guides to using of therapies aimed at neutralizing the severe inflammatory response. A timely diagnosis would allow prompt treatment and minimize complications.
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关键词
Child,Ferritin,Hemophagocytic,Human immunodeficiency virus,Lymphohistiocytosis,Sepsis
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