Low-Dose Whole Brain Radiation Therapy for Alzheimer's Dementia: Results From a Pilot Trial in Humans

C. Leland Rogers,Sarah K. Lageman,James Fontanesi,George D. Wilson, Peter A. Boling, Surbhi Bansal,John P. Karis,Marwan Sabbagh,Minesh P. Mehta,Timothy J. Harris

International journal of radiation oncology, biology, physics（2023）

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摘要

Our results from 5 patients with eAD treated with LD-WBRT (10 Gy in 5 fractions) demonstrate a positive safety profile and provide preliminary, hypothesis-generating data to suggest that this treatment stabilizes or improves cognition. These findings will require further evaluation in larger, definitive, randomized trials.

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