Antiphospholipid antibodies in patients with stroke during COVID-19: A role in the signaling pathway leading to platelet activation.

Antonella Capozzi,Gloria Riitano,Serena Recalchi,Valeria Manganelli,Agostina Longo,Anne Falcou,Manuela De Michele,Tina Garofalo,Fabio M Pulcinelli,Maurizio Sorice,Roberta Misasi

Frontiers in immunology（2023）

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摘要

This study demonstrates the presence of aPLs in a subgroup of COVID-19 patients who presented AIS, suggesting a role in the mechanisms contributing to hypercoagulable state in these patients. Detecting these antibodies as a serological marker to check and monitor COVID-19 may contribute to improve the risk stratification of thromboembolic manifestations in these patients.

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关键词

COVID-19,antiphospholipid antibodies,stroke.,thrombosis,β2-GPI

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