Correlation of tumor mutational burden with prognosis and immune infiltration in lung adenocarcinoma.
Frontiers in oncology（2023）
摘要
The survival rate of LUAD patients with low TMB was better than that of LUAD patients with high TMB. CD274 expression was down regulated in human LUAD cell lines H1299, PC-9, A549 and SPC-A1, which inhibited malignant progression of A549 cells.
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关键词
cell proliferation,immune checkpoint blockade,lung adenocarcinoma,the cancer genome atlas,tumor mutation burden
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