Loss of Müller cell glutamine synthetase immunoreactivity is associated with neuronal changes in late-stage retinal degeneration.

Hallur Reynisson,Michael Kalloniatis,Erica L Fletcher,Mohit N Shivdasani,Lisa Nivison-Smith

Frontiers in neuroanatomy（2023）

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摘要

These findings further support a strong interplay between glia-neuronal alterations in late-stage degeneration and highlight a need for future studies and consideration in intervention development.

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关键词

Müller cells,glutamine synthetase,neurodegeneration,photoreceptor degeneration,rd1 mouse model,retinal remodeling

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