Supplementary Figures 1 - 9 from Oncogenic Protein MTBP Interacts with MYC to Promote Tumorigenesis

PDF file - 687KB, Supplemental Figures S1-S9. S1 shows MTBP induces proliferation. S2 shows peptides in TIP48 and TIP49 identified by mass spectrometry. S3 shows Mtbp increases the pro-proliferative and transforming functions of Myc. S4 shows increased MTBP and MYC express correlates with poor colon and lung cancer survival. S5 shows the location of MTBP and MYC on 8q24. S6 shows Mtbp knockdown inhibits Myc-mediated transcription. S7 shows MTBP knockdown inhibits proliferation. S8 shows the C-terminus of Mtbp inhibits breast cancer cell expansion. S9 shows the working model of MTBP function.