MicroRNAs of extracellular vesicles derived from mesenchymal stromal cells alleviate inflammation in dry eye disease by targeting the IRAK1/TAB2/NF-κB pathway.

Leying Wang,Xueyao Wang,Qiankun Chen,Zhenyu Wei,Xizhan Xu,Deqiang Han,Yuheng Zhang,Zhiguo Chen,Qingfeng Liang

The ocular surface（2023）

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摘要

hucMSCs-EVs alleviate DED signs, suppress inflammation and restore homeostasis of the corneal surface by multitargeting the IRAK1/TAB2/NF-κB pathway via certain miRNAs.

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关键词

Dry eye,Extracellular vesicles,Immunomodulatory,Mesenchymal stromal cells,Treatment

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