Comparative Analysis of the Interaction of Silver Nanoparticles with Hexokinase from Trypanosoma brucei and Humans.

Madalitso M Mlozen, Jacqueline Van Marwijk,Brendan Shane Wilhelmi,Chris Whiteley

International journal of nanomedicine（2023）

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摘要

The observed pattern of hGCK and AgNPs falls under the uncompetitive inhibition. The observed highly selective inhibitory effects of AgNPs between HK and GCK may be used in development of new anti-trypanosomal drugs.

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hexokinase,nanomedicine,nanoparticles,trypanosomiasis

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