Supplementary Figure S1 from Validation of the 16-Gene Recurrence Score in Patients with Locoregional, High-Risk Renal Cell Carcinoma from a Phase III Trial of Adjuvant Sunitinib

The gene/gene groups and algorithm included in calculating the RS. The RS is derived from the reference-normalized expression measurements, scaled from 0 to 100: Unscaled RS = -0.45 Ã- VN group score -0.31 Ã- IR group score + 0.27 Ã- CGD group score + 0.04 Ã- IL6. RS = 26.4 Ã- (unscaled RS + 3.7). The score is scaled: if RS is <0, then RS=0; and if RS is >100, then RS=100. Abbreviation: RS, recurrence score.