Combined Effects of Focused Ultrasound and Photodynamic Treatment for Malignant Brain Tumors Using C6 Glioma Rat Model.

Junwon Park,Chanho Kong,Jaewoo Shin, Ji Young Park,Young Cheol Na,Seung Hee Han,Jin Woo Chang,Seung Hyun Song,Won Seok Chang

Yonsei medical journal（2023）

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摘要

Our findings show that light with sensitizers can inhibit GBM growth, but not ultrasound. Although SPDT did not show the combined effect in MRI, high oxidative stress was observed in IHC. Further studies are needed to investigate the safety parameters to apply ultrasound in GBM.

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关键词

Focused ultrasound,glioblastoma,photodynamic therapy,sono-photodynamic therapy,sonodynamic therapy,treatment

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