Blood and Site of Disease Inflammatory Profiles Differ in Patients With Pericardial Tuberculosis and Human Immunodeficiency Virus Type 1.

Hygon Mutavhatsindi,Elsa Du Bruyn,Sheena Ruzive,Patrick Howlett,Maddalena Cerrone,Alan Sher,Katrin D Mayer-Barber,Daniel L Barber,Mpiko Ntsekhe,Robert J Wilkinson,Catherine Riou

Open forum infectious diseases（2023）

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摘要

Our results show that the inflammatory profile in blood was comparable between PTB and PCTB. However, at the site of infection (PCF), inflammation was significantly elevated compared to blood. Additionally, our data emphasize the potential role of HLA-DR expression as a biomarker for TB diagnosis.

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关键词

diagnosis,inflammatory profile,pericardial tuberculosis,site of disease,treatment response

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