Eosinophils promote effector functions of lung ILC2s in allergic airway inflammation in mice

William E. LeSuer,Melanie Kienzl,Sergei I. Ochkur,Rudolf Schicho,Alfred D. Doyle,Benjamin L. Wright,Matthew A. Rank,Alexander S. Krupnick,Hirohito Kita,Elizabeth A. Jacobsen

Journal of Allergy and Clinical Immunology（2023）

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摘要

These studies demonstrate eosinophils play a reciprocal role in ILC2 effector functions as part of both adaptive and innate type 2 pulmonary inflammatory events.

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关键词

Eosinophil,IL-13,IL-33,IL-4,asthma,eosinophil-deficient,group 2 innate lymphoid cell,inflammation,lung

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