Primary Non-Hodgkin's Lymphoma of the Nose: A Rare Case Report

Extranodal NK/T-cell lymphoma, nasal type (ENKL) is a rare nasal pathology, which in the past was grouped with list of granulomatous diseases. It is an aggressive non-Hodgkin's lymphoma characterized clinically by a non-relenting destruction of the midline structures of the palate and nasal cavity. Despite the malignant clinical nature, tissue diagnosis may be difficult due to extensive tissue necrosis mandating multiple biopsies and has an ominous prognosis, as the average survival rate lying between 6 and 25 months as in large number of Asian studies. This is the case report of a 60-year-old female who presented with (L) nasal obstruction and recurrent episodes of rhinosinusitis for last 8 months, which had been treated with antibiotics, anti-inflammatory drugs and intranasal corticosteroids without success. After performing battery of tests, diagnosed histologically and confirmed by immunohistochemical analysis that the patient had an ENKL, nasal type (AKA angiocentric T-cell lymphoma).