A Ph/cellulase Dual Stimuli-Responsive Cellulose-Coated Metal–organic Framework for Eco-Friendly Fungicide Delivery

•A controlled-release pesticide formulation PYR@UiO-66@HPC was successfully fabricated by encapsulating PYR within a metal–organic framework and coating with HPC.•Release experiments demonstrated that PYR@UiO-66@HPC exhibits pH/cellulase dual stimuli-responsive behavior for the intelligent delivery of pyraclostrobin.•The PYR@UiO-66@HPC exhibited an excellent fungicidal activity and a low toxicity toward non-target organisms.•The PYR@UiO-66@HPC did not affect the normal growth of the target rice crop and it had a low impact on the soil microbial community.